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Alain Bruhat

Researcher at Institut national de la recherche agronomique

Publications -  64
Citations -  9717

Alain Bruhat is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Amino acid & Gene expression. The author has an hindex of 35, co-authored 61 publications receiving 8841 citations. Previous affiliations of Alain Bruhat include University of Auvergne.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

Wafa B'chir, +9 more
- 01 Sep 2013 - 
TL;DR: A novel regulatory role of the eIF2α–ATF4 pathway is revealed in the fine-tuning of the autophagy gene transcription program in response to stresses.
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Amino acid regulation of gene expression.

Pierre Fafournoux, +2 more
- 01 Oct 2000 - 
TL;DR: The results discussed in this review demonstrate that amino acids by themselves can play, in concert with hormones, an important role in the control of gene expression.
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Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation.

Julien Averous, +5 more
- 13 Feb 2004 - 
TL;DR: In this article, a genomic cis-acting element (amino acid response element (AARE) was found to be involved in the transcriptional activation of the human CHOP gene by leucine starvation and shown that it binds the activating transcription factor 2 (ATF2).
Journal ArticleDOI

Amino Acid Limitation Induces Expression of CHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

Alain Bruhat, +5 more
- 11 Jul 1997 - 
TL;DR: The role of amino acid limitation in regulating the expression of CHOP, a CCAAT/enhancer binding protein (C/EBP)-related gene, is examined and it is found that decreasing amino acid concentration by itself can induce CHOP expression independently of a cellular stress due to protein synthesis inhibition.