Miriam J. Schönenberger

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Current knowledge of how HIF-α signaling regulates the abundance and function of major O2-consuming organelles is critically explored and potential mechanisms by which Hif-2α might trigger pexophagy are discussed and a mechanism by which cells attune peroxisomal function with O2 availability is suggested.

TL;DR: Hif-2α is established as a negative regulator of peroxisome abundance and metabolism and a mechanism by which cells attune peroxISomal function with oxygen availability is suggested.

TL;DR: High expression levels and acute, profound hypoxic induction of MALAT1 suggest a hitherto unrecognized role of this lncRNA in renal proximal tubular function, as well as exploring the conditional regulation of lncRNAs in genome-wide studies.