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Eldad Zacksenhaus

Researcher at University of Toronto

Publications -  115
Citations -  9661

Eldad Zacksenhaus is an academic researcher from University of Toronto. The author has contributed to research in topics: Retinoblastoma protein & Cancer. The author has an hindex of 35, co-authored 102 publications receiving 8674 citations. Previous affiliations of Eldad Zacksenhaus include Roswell Park Cancer Institute & University Health Network.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

Eldad Zacksenhaus, +5 more
- 01 Dec 1996 - 
TL;DR: A role for pRb during terminal differentiation of skeletal muscles in vivo is demonstrated and pRB is placed at a nodal point that controls cell proliferation, differentiation, and death.
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Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies.

Diane Rushlow, +26 more
- 01 Apr 2013 - 
TL;DR: These unilateral RB1(+/+)MYCN(A) retinoblastomas are characterised by distinct histological features, only a few of the genomic copy-number changes that are characteristic of retinOBlastoma, and very early age of diagnosis.
Journal Article

The retinoblastoma protein and the cell cycle.

Sopta M, +6 more
- 01 Jun 1992 - 
TL;DR: The role of RB1 mutation in cancer initiation is highly restricted to the rare embryonic tumor, retinoblastoma, but RB1 is expressed and its product, p110RB1, is regulated through the cell cycle in many tissues.
Journal ArticleDOI

Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors.

Jeff C. Liu, +4 more
- 15 Sep 2007 - 
TL;DR: The functional identification of mouse HER2/Neu TICs that can induce tumors after transplantation into the mammary gland of recipient mice is reported on, which help to explain marker expression profiles of HER2-positive breast cancer.