Marco Tucci

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The identification of specific mutations in target genes can aid in therapeutic decisions, both in the appropriateness of treatment and in the advanced identification of secondary resistance, aiming to early diagnose disease progression.

TL;DR: It is suggested that the high level of expression of IL-18R by peripheral plasmacytoid DCs allows the DCs to relocate within glomeruli under IL- 18 stimulation and triggers the resident T cells, thus promoting renal damage.

TL;DR: Current advances in cancer immunoediting are reviewed and focus on melanoma immunology, which involves a dynamic interplay between melanoma and immune system, as well as on effects of “targeted therapies” on tumor microenvironment for combination strategies.

TL;DR: At can be considered an option for patients with indolent lymphomas who do not need immediate cytoreductive treatment and used at any time is associated with improved OS.