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Jörn Coers

Researcher at Duke University

Publications -  75
Citations -  9066

Jörn Coers is an academic researcher from Duke University. The author has contributed to research in topics: Intracellular parasite & Chlamydia trachomatis. The author has an hindex of 34, co-authored 62 publications receiving 7944 citations. Previous affiliations of Jörn Coers include Yale University & German Cancer Research Center.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

TL;DR: It is demonstrated that IFN-inducible guanylate binding protein (Gbp) proteins stimulate caspase-11–dependent, cell-autonomous immunity in response to cytoplasmic LPS, and a role is suggested for Gbpchr3 proteins in the detection of cy toplasmo LPS and the activation of the noncanonical inflammasome.
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Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth.

TL;DR: Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth that contributes to cell proliferation and cell reprograming.
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Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth.

TL;DR: Data show that, in addition to genes that encode the core Dot/Icm transport apparatus, subsets of genes are required for pore formation and modulation of phagosome trafficking, which supports a model in which the IcmQ–IcmR complex regulates the formation of a translocation channel that delivers proteins into host cells.