Joan K. Heath

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: A model whereby mucosal wound healing depends solely on activation of STAT1/3, whereas gastric hyperplasia ensues when the coordinated activation of the STAT1-3 and SHP2-Ras-ERK pathways is disrupted is proposed.

TL;DR: In this article, the morphological events that shape the zebrafish intestinal epithelium were investigated. But the authors focused on the period between 26 and 126 h post-fertilization (hpf) and followed the growth, lumen formation and differentiation of a continuous layer of endoderm into a functional intestinal epithelial with three morphologically distinct segments: the intestinal bulb, mid-intestine and posterior intestine.

TL;DR: For osteoblastic cells in culture, E2 can directly stimulate proliferation as well as collagen and IGF-I mRNA while decreasing PTH responsiveness; these effects could explain the anabolic and anticatabolic effects of E2 on bone.

TL;DR: It is shown that lymph node stromal cells present endogenously expressed PTAs to T cells and provide a direct strategy for purging the peripheral repertoire of self-reactive T cells.