Mikkel H. Vendelbo

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Ketone bodies displace MGU and increase myocardial blood flow in healthy humans; these novel observations suggest that ketone bodies are important cardiac fuels and vasodilators, which may have therapeutic potentials.

TL;DR: The results support that in training‐accustomed individuals, mTORC1 signaling is preferentially activated after hypertrophy‐inducing exercise, while AMPK signaling is less specific for differentiated exercise.

TL;DR: It is demonstrated that autophagy signaling is activated in human skeletal muscle after 60 min of exercise, independently of nutritional status, and suggested that initiation of autophagic constitutes an important physiological response to exercise in humans.

TL;DR: W Whole-body PET revealed that 11C-metformin was primarily taken up by the kidneys, urinary bladder, and liver but also to a lesser extent in salivary glands, skeletal muscle, and intestines; and tissue kinetics showed only discrete tracer uptake.