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Hélène Duez

Researcher at Pasteur Institute

Publications -  80
Citations -  12317

Hélène Duez is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Circadian rhythm & Insulin resistance. The author has an hindex of 40, co-authored 72 publications receiving 11069 citations. Previous affiliations of Hélène Duez include Lille University of Science and Technology & University of Toronto.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Protective role of interleukin-10 in atherosclerosis

TL;DR: It is shown that IL-10-deficient C57BL/6J mice fed an atherogenic diet and raised under specific pathogen-free conditions exhibit a significant 3-fold increase in lipid accumulation compared with wild-type mice, which underscores the critical roles ofIL-10 in both atherosclerotic lesion formation and stability.
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Peroxisome Proliferator-Activated Receptors and Atherogenesis: Regulators of Gene Expression in Vascular Cells

TL;DR: The role of PPARs in the vasculature is focused on and the present understanding of their effects on atherogenesis and its cardiovascular complications is summarized.
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Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-I

TL;DR: Observations provide a molecular basis for combination treatment with statins and fibrates in coronary heart disease and identify a statin response element that coincides with a PPARalpha response element known to confer fibrate responsiveness to this gene.
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Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.

TL;DR: It is shown that Rev-erb-α is highly expressed in oxidative skeletal muscle and that its deficiency in muscle leads to reduced mitochondrial content and oxidative function, as well as upregulation of autophagy, which results in compromised exercise capacity.