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Natalia Rodriguez-Muela

Researcher at Spanish National Research Council

Publications -  25
Citations -  7168

Natalia Rodriguez-Muela is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 17, co-authored 20 publications receiving 6392 citations. Previous affiliations of Natalia Rodriguez-Muela include Harvard University & German Center for Neurodegenerative Diseases.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Pathogenic Lysosomal Depletion in Parkinson's Disease

Benjamin Dehay, +6 more
- 15 Sep 2010 - 
TL;DR: It is found in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of PD that AP accumulation and dopaminergic cell death are preceded by a marked decrease in the amount of lysosomes within dopamine neurons, indicating that restoration of lYSosomal levels and function may represent a novel neuroprotective strategy in PD.
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Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

Natalia Rodriguez-Muela, +5 more
- 01 Jan 2012 - 
TL;DR: The data support that autophagy has a cytoprotective role in RGCs after traumatic injury and may provide a new therapeutic strategy to ameliorate retinal diseases.
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Balance between autophagic pathways preserves retinal homeostasis.

Natalia Rodriguez-Muela, +6 more
- 01 Jun 2013 - 
TL;DR: A marked reduction in macroautophagic activity in the retina with age is described, which coincides with an increase in chaperone‐mediated autophagy (CMA), which is also observed during retinal neurodegeneration in the Atg5flox/flox mice and nestin‐Cre mice.
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Autophagy in stem cells: repair, remodelling and metabolic reprogramming.

Patricia Boya, +2 more
- 15 Feb 2018 - 
TL;DR: The role of autophagy in embryonic, adult and cancer stem cells and cellular reprogramming is summarized, and the consequences of Autophagy dysregulation on tissue development and homeostasis are highlighted.