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Atsushi Kuno

Researcher at Sapporo Medical University

Publications -  93
Citations -  8705

Atsushi Kuno is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Resveratrol & Internal medicine. The author has an hindex of 32, co-authored 78 publications receiving 7712 citations. Previous affiliations of Atsushi Kuno include Okayama University of Science & University of South Alabama.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure.

TL;DR: Oral administration of resveratrol to TO-2 hamsters increased Mn-SOD levels in cardiomyocytes, suppressed fibrosis, preserved cardiac function, and significantly improved survival, suggesting SIRT1 activators such as resver atrol could be novel therapeutic tools for the treatment of chronic heart failure.
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Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

TL;DR: The results indicate that FOXO1, FOXO3a and FOXO4, are indispensable for Sirt1-dependent cell survival against oxidative stress, although deacetylation of p53 has also some role for cell protective function of SIRT1.
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Opening of mitochondrial KATP channel occurs downstream of PKC-ε activation in the mechanism of preconditioning

TL;DR: This work examined whether the mitochondrial ATP-sensitive K channel (KATP) is an effector downstream of protein kinase C-e (PKC-e) in the mechanism of preconditioning in isolated rabbit hearts.