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Shingo Kajimura

Researcher at Beth Israel Deaconess Medical Center

Publications -  130
Citations -  27082

Shingo Kajimura is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Adipose tissue & Brown adipose tissue. The author has an hindex of 54, co-authored 117 publications receiving 22708 citations. Previous affiliations of Shingo Kajimura include University of Tokyo & Harvard University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, +17 more
- 26 Jan 2012 - 
TL;DR: This article showed that PGC1α expression in muscle stimulates an increase in expression of FNDC5, a membrane protein that is cleaved and secreted as a newly identified hormone, irisin.
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PRDM16 controls a brown fat/skeletal muscle switch

Patrick Seale, +13 more
- 21 Aug 2008 - 
TL;DR: It is shown by in vivo fate mapping that brown, but not white, fat cells arise from precursors that express Myf5, a gene previously thought to be expressed only in the myogenic lineage.
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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

Patrick Seale, +8 more
- 04 Jan 2011 - 
TL;DR: It is demonstrated that Prdm16 is a cell-autonomous determinant of a brown fat-like gene program and thermogenesis in subcutaneous adipose tissues and reduced the brown fat phenotype in white adipose tissue stimulated by β-adrenergic agonists.
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Transcriptional Control of Brown Fat Determination by PRDM16

Patrick Seale, +10 more
- 11 Jul 2007 - 
TL;DR: It is shown here that the zinc-finger protein PRDM16 is highly enriched in brown fat cells compared to white fat cells, indicating that PRDM 16 can control the determination of brown fat fate.