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Robert C. Dickson

Researcher at University of Kentucky

Publications -  110
Citations -  13642

Robert C. Dickson is an academic researcher from University of Kentucky. The author has contributed to research in topics: Saccharomyces cerevisiae & Sphingolipid. The author has an hindex of 52, co-authored 104 publications receiving 12898 citations. Previous affiliations of Robert C. Dickson include Sichuan University & St. Joseph's Healthcare Hamilton.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Biochemistry, Cell Biology and Molecular Biology of Lipids of Saccharomyces cerevisiae

TL;DR: Current knowledge about lipid biosynthetic pathways in S. cerevisiae is summarized and characteristic features of the gene products involved are described, focusing on recent discoveries in these fields.
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Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

TL;DR: The data suggest that sphingosine kinase is a prototypical member of a new class of lipid kinases, and an important step in corroborating the intracellular role of SPP as a second messenger.
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Sphingolipid Synthesis as a Target for Antifungal Drugs: COMPLEMENTATION OF THE INOSITOL PHOSPHORYLCERAMIDE SYNTHASE DEFECT IN A MUTANT STRAIN OF SACCHAROMYCES CEREVISIAE BY THE AUR1 GENE *

TL;DR: A gene, AUR1 (YKL004w), that complements the IPC synthase defect and restores enzyme activity and sphingolipid synthesis was isolated, showing that the drug is a potent inhibitor of I PC synthase with an IC50 of about 0.2 nM.
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Sphingolipid functions in Saccharomyces cerevisiae: comparison to mammals.

TL;DR: Saccharomyces cerevisiae is likely to be the first organism in which all genes involved in sphingolipid metabolism are identified, and this information will provide an unprecedented opportunity to determine, for the first time in any organism, how sphingoipid synthesis is regulated.