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Katsuhiko Mikoshiba

Researcher at ShanghaiTech University

Publications -  874
Citations -  65750

Katsuhiko Mikoshiba is an academic researcher from ShanghaiTech University. The author has contributed to research in topics: Inositol trisphosphate receptor & Inositol. The author has an hindex of 120, co-authored 866 publications receiving 62394 citations. Previous affiliations of Katsuhiko Mikoshiba include Toho University & University of Tokyo.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

TL;DR: The development of an improved version of YFP named Venus, which contains a novel mutation, F46L, which at 37°C greatly accelerates oxidation of the chromophore, the rate-limiting step of maturation and will enable fluorescent labelings that were not possible before.
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'Ischemic tolerance' phenomenon found in the brain

TL;DR: 'ischemic tolerance' phenomenon induced by ischemic stress--which is unquestionably important--and frequent stress in clinical medicine, is intriguing and may open a new approach to investigate the pathophysiology of isChemic neuronal damage.
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Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.

TL;DR: Cloning and expression of functional P400 protein from cerebellar Purkinje neurons shows that this protein is a receptor for inositol 1,4,5-triphosphate, a second messenger that mediates the release of intracellular calcium.
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2APB, 2-Aminoethoxydiphenyl Borate, a Membrane-Penetrable Modulator of Ins(1,4,5)P3-Induced Ca2+ Release

TL;DR: Although the specificity of 2APB with respect to the intracellular signaling system was not fully established, it is the first candidate for a membrane-penetrable modulator of Ins(1,4,5)P3 receptor, and it should be a useful tool to investigate the physiological role of the Ins(2,3,3)P2 receptor in various cells.