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Armando A. Genazzani

Researcher at University of Eastern Piedmont

Publications -  252
Citations -  15929

Armando A. Genazzani is an academic researcher from University of Eastern Piedmont. The author has contributed to research in topics: Receptor & Ryanodine receptor. The author has an hindex of 53, co-authored 231 publications receiving 14016 citations. Previous affiliations of Armando A. Genazzani include Sapienza University of Rome & University of Milan.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.

TL;DR: The present review will outline the accomplishments of the 1,3‐dipolar cycloaddition (“click‐reaction”) between azides and alkynes catalyzed by copper (I) salts and outline some of medicinal chemistry applications in which click‐chemistry might be relevant in the future.
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Medicinal chemistry of combretastatin A4: present and future directions.

TL;DR: The present review will concentrate primarily on the medicinal chemistry of one of these drugs, combretastatin A4 (CA-4 a), which has been brought forward into the drug pipeline that share this mechanism of action.
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NAADP Mobilizes Ca2+ from Reserve Granules, Lysosome-Related Organelles, in Sea Urchin Eggs

TL;DR: The presence of a Ca 2+ store in sea urchin eggs mobilized by NAADP that is dependent on a proton gradient maintained by an ATP-dependent vacuolar-type proton pump is demonstrated, representing an unsuspected mechanism for messenger-mediated Ca 2+, release from lysosome-related organelles.
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Applications of Deuterium in Medicinal Chemistry

TL;DR: This Perspective provides an overview of the recent developments of deuteration, with a focus on deuterated clinical candidates, and highlights both opportunities and challenges of this strategy.