scispace - formally typeset
D

Daniel E. Frigo

Researcher at University of Houston

Publications -  56
Citations -  7797

Daniel E. Frigo is an academic researcher from University of Houston. The author has contributed to research in topics: Prostate cancer & Androgen receptor. The author has an hindex of 30, co-authored 46 publications receiving 6870 citations. Previous affiliations of Daniel E. Frigo include Durham University & Tulane University.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

Jun Hyoung Park, +26 more
- 08 Mar 2016 - 
TL;DR: Analysis of cybrids and established breast cancer cell lines showed that metastatic TNBC maintains high levels of ATP through fatty acid β oxidation (FAO) and activates Src oncoprotein through autophosphorylation at Y419, and confirmed the role of mitochondrial FAO in Src activation and metastasis.
Journal ArticleDOI

Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

Andrea B. Sherk, +11 more
- 15 Sep 2008 - 
TL;DR: It is determined that RNA interference-mediated knockdown of SGK1 expression attenuates the androgen-mediated growth of the prostate cancer cell line LNCaP, and in addition to androgen ablation, inhibition of pathways downstream of AR is likely to have therapeutic utility in prostate cancer.
Journal ArticleDOI

Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.

Jayantha B. Tennakoon, +13 more
- 06 Nov 2014 - 
TL;DR: It is demonstrated that androgens can co-opt the AMPK-PGC-1α signaling cascade, a known homeostatic mechanism, to increase prostate cancer cell growth.
Journal ArticleDOI

CaM kinase kinase β-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

Daniel E. Frigo, +8 more
- 15 Jan 2011 - 
TL;DR: Using cellular models of prostate cancer, it is determined that androgens directly increase the expression of a CaMKKβ splice variant and increase functional CaMkkβ protein levels as determined by the phosphorylation of both CaMKI and AMP-activated protein kinase (AMPK), two of CaMikkβ's primary substrates.