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Valerie B. O'Donnell

Researcher at Cardiff University

Publications -  176
Citations -  18040

Valerie B. O'Donnell is an academic researcher from Cardiff University. The author has contributed to research in topics: Platelet activation & Inflammation. The author has an hindex of 53, co-authored 159 publications receiving 14428 citations. Previous affiliations of Valerie B. O'Donnell include University of Bristol & University of Alabama at Birmingham.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, +28 more
- 01 Dec 2014 - 
TL;DR: It is demonstrated that ferroptosis is a pervasive and dynamic form of cell death, which, when impeded, promises substantial cytoprotection.
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FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll, +31 more
- 21 Oct 2019 - 
TL;DR: The FSP1–CoQ10–NAD(P)H pathway exists as a stand-alone parallel system, which co-operates with GPX4 and glutathione to suppress phospholipid peroxidation and ferroptosis in cells.
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Expression of phagocyte NADPH oxidase components in human endothelial cells.

Simon Arnett Jones, +5 more
- 01 Oct 1996 - 
TL;DR: Data indicate that cultured human endothelial cells express both mRNA and protein for cytosolic components of the phagocyte superoxide-generating NADPH oxidase, suggesting that a contribution of this enzyme to endothelial oxidant generation may be unlikely.
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Inflammation and immune regulation by 12/15-lipoxygenases.

Hartmut Kühn, +1 more
- 01 Jul 2006 - 
TL;DR: The biochemistry and tissue expression of 12/15-LOX is summarized, the current knowledge regarding its immunobiology and regulation of inflammation is described and the biochemical mechanisms by which it regulates physiological and pathological immune cell function are described.