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Balakrishna L. Lokeshwar

Researcher at Georgia Regents University

Publications -  50
Citations -  8075

Balakrishna L. Lokeshwar is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Cancer & LNCaP. The author has an hindex of 23, co-authored 45 publications receiving 7410 citations. Previous affiliations of Balakrishna L. Lokeshwar include State University of New York System & University of Miami.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25- hydroxyvitamin D3

TL;DR: Two of three human prostate cancer cell lines, as well as primary cultures of noncancerous prostatic cells, possess 1alpha-hydroxylase activity and can synthesize 1,25(OH)2D3 from 25-OH-D3, suggesting a potential role in the chemoprevention of invasive prostate cancer.
Journal Article

Tear fluid gelatinase B activity correlates with IL-1α concentration and fluorescein clearance in ocular rosacea

TL;DR: Elevated gelatinase B activity in ocular rosacea may be involved in the pathogenesis of the irritation symptoms, recurrent epithelial erosions, vascularization, and epithelial basement membrane dystrophy that develops in the corneas of patients with this condition.
Journal ArticleDOI

Regulation of MMP-9 Production by Human Corneal Epithelial Cells

TL;DR: Production of MMP-9 is stimulated by the pro-inflammatory cytokines, IL-1beta and TNF-alpha, and these factors may play a role in the pathogenesis of M MP-9 mediated corneal matrix degradation.
Journal Article

A mouse model of keratoconjunctivitis sicca.

TL;DR: Pharmacologic inhibition of tear production in mice is accompanied by ocular surface epithelial changes resembling human keratoconjunctivitis sicca (KCS) that are exacerbated by desiccating environmental stress.