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Manish K. Aghi

Researcher at University of California, San Francisco

Publications -  363
Citations -  18095

Manish K. Aghi is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 54, co-authored 297 publications receiving 14862 citations. Previous affiliations of Manish K. Aghi include University of Texas Southwestern Medical Center & Residence Inn by Marriott.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

Kan V. Lu, +11 more
- 10 Jul 2012 - 
TL;DR: It is demonstrated that vascular endothelial growth factor (VEGF) directly and negatively regulates tumor cell invasion through enhanced recruitment of the protein tyrosine phosphatase 1B to a MET/VEGFR2 heterocomplex, thereby suppressing HGF-dependent MET phosphorylation and tumor cell migration.
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Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

Sören Müller, +15 more
- 20 Dec 2017 - 
TL;DR: It is concluded that blood-derived TAMs significantly infiltrate pre-treatment gliomas, to a degree that varies by glioma subtype and tumor compartment, and a novel signature that distinguishes TAMs by ontogeny in humangliomas is presented.
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Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

Yu-Long Hu, +6 more
- 01 Apr 2012 - 
TL;DR: The hypothesis that hypoxia caused by antiangiogenic therapy induces tumor cell autophagy as a cytoprotective adaptive response, thereby promoting treatment resistance is explored, and a novel mechanism of resistance to antiangIogenic therapy in which Hypoxia-mediatedautophagy promotes tumor cell survival is elucidated.
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Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation.

Manish K. Aghi, +7 more
- 01 Jan 2009 - 
TL;DR: After GTR without postoperative radiation, AMs have a high recurrence rate, and most recurrences occurred within 5 years after resection, suggesting lower recurrence rates in patients undergoing immediate postoperative Radiation should be investigated in larger, prospective series.