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Sasanka Ramanadham

Researcher at University of Alabama at Birmingham

Publications -  104
Citations -  9698

Sasanka Ramanadham is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Phospholipase A2 & Pancreatic islets. The author has an hindex of 40, co-authored 94 publications receiving 9021 citations. Previous affiliations of Sasanka Ramanadham include University of Washington & University of Birmingham.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Biochemical Evidence for Nitric Oxide Formation from Streptozotocin in Isolated Pancreatic Islets

John Turk, +4 more
- 30 Dec 1993 - 
TL;DR: Data presented here indicate that incubation of rat islets with STZ at concentrations that impair insulin secretion results in generation of nitrite, stimulation of islet guanylyl cyclase and accumulation of cGMP, and inhibition of islets mitochondrial aconitase activity to a degree similar to that achieved by IL-1.
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Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.

Shunzhong Bao, +7 more
- 10 Sep 2004 - 
TL;DR: It is indicated that iPLA2β plays an important functional role in spermatozoa, suggest a target for developing male contraceptive drugs, and complement reports that disruption of the Group IVA PLA2 (cPLA2α) gene impairs female reproductive ability.
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Calcium-independent phospholipases A2 and their roles in biological processes and diseases.

Sasanka Ramanadham, +5 more
- 01 Sep 2015 - 
TL;DR: The iPLA2s manifest a variety of activities in addition to phospholipase, are ubiquitously expressed, and participate in a multitude of biological processes, including fat catabolism, cell differentiation, maintenance of mitochondrial integrity,ospholipid remodeling, cell proliferation, signal transduction, and cell death.
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Long-Term Effects of Vanadyl Treatment on Streptozocin-Induced Diabetes in Rats

Raymond A. Pederson, +3 more
- 01 Nov 1989 - 
TL;DR: It is shown that short-termVanadyl treatment of STZ-D rats yields normalization of glucose tolerance and protection of islets from destruction by STZ, and the relationship between normal glucose tolerance, normal islet insulin content, and reduced insulin secretion in vanadyl-treated STZ -D rats remains to be investigated.