Dong-Yun Ouyang

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Cisplatin induced higher levels of secondary necrosis/pyroptosis in A549 cells than paclitaxel, suggesting that cisplatin may provide additional advantages in the treatment of lung cancers with high levels of GSDME expression.

TL;DR: Results indicated that VPA-induced autophagy in prostate cancer cells depended on ATG5 and more importantly, that the Autophagy pathway was genetically impaired in DU145 cells, suggesting caution in interpreting autophagic responses in this cell line.

TL;DR: Results indicated that piperine exhibited anti-proliferative effect in human prostate cancer cells by inducing cell cycle arrest and autophagy.

TL;DR: The results showed that scutellarin dose-dependently reduced caspase-1 activation and decreased mature interleukin-1β release in lipopolysaccharide (LPS)-primed macrophages upon ATP or nigericin stimulation, indicating that scUTellarin inhibited NLRP3 inflammasome activation in macrophage.