Kelsey B. Law

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Results suggest that NBR1 is the specific autophagy receptor for pexophagy, and that substrate selectivity is partly achieved by N BR1 itself by coincident binding of the J and UBA domains to peroxisomes.

TL;DR: It is shown here that loss of the AAA-complex does not prevent matrix protein import, but instead causes an upregulation of peroxisome degradation by macroautophagy, or pexophagy.