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Kwang Woon Kim

Researcher at Vanderbilt University

Publications -  43
Citations -  8120

Kwang Woon Kim is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 30, co-authored 43 publications receiving 7551 citations. Previous affiliations of Kwang Woon Kim include Pusan National University & Vanderbilt University Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inhibition of Mammalian Target of Rapamycin or Apoptotic Pathway Induces Autophagy and Radiosensitizes PTEN Null Prostate Cancer Cells

Carolyn Cao, +7 more
- 15 Oct 2006 - 
TL;DR: Testing the ability of the mTOR inhibitor RAD001 (everolimus) to enhance the cytotoxic effects of radiation on two prostate cancer cell lines found that both cell lines became more vulnerable to irradiation after treatment with RAD001, with the PTEN-deficient PC-3 cell line showing the greater sensitivity.
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Inhibition of Poly(ADP-Ribose) Polymerase Enhances Cell Death and Improves Tumor Growth Delay in Irradiated Lung Cancer Models

Jeffrey M. Albert, +12 more
- 15 May 2007 - 
TL;DR: It is concluded that PARP-1 inhibition shows promise as an effective means of enhancing tumor sensitivity to radiation, and future clinical studies are needed to determine the potential of ABT-888 as a radiation enhancer.
Journal ArticleDOI

Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

Kwang Woon Kim, +6 more
- 01 Dec 2006 - 
TL;DR: This is the first report to demonstrate that inhibition of pro-apoptotic proteins and induction of autophagy sensitizes cancer cells to therapy and Therapeutically targeting this novel pathway may yield significant benefits for cancer patients.
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Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

Jeffrey M. Albert, +3 more
- 01 May 2006 - 
TL;DR: It is concluded that RAD001 attenuates radiation-induced prosurvival Akt/mTOR signaling and enhances the cytotoxic effects of radiation in breast cancer cell models, showing promise as a method of radiosensitization of breast cancer.