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Kevin A. Roth

Researcher at University of Alabama at Birmingham

Publications -  205
Citations -  17317

Kevin A. Roth is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 68, co-authored 204 publications receiving 16457 citations. Previous affiliations of Kevin A. Roth include PerkinElmer & Dalhousie University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Ethanol-induced caspase-3 activation in the in vivo developing mouse brain.

John W. Olney, +6 more
- 01 Mar 2002 - 
TL;DR: Using immunocytochemical methods, it is documented that ethanol intoxication of 7-day-old infant mice causes a widespread pattern of caspase-3 activation corresponding to the pattern of apoptotic neurodegeneration that is occurring simultaneously.
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Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

Liyan Qiao, +23 more
- 21 Nov 2008 - 
TL;DR: The data identify a conserved CD function in α-syn degradation and identify CD as a novel target for LB disease therapeutics.
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Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease.

Karen E. Weck, +7 more
- 01 Dec 1997 - 
TL;DR: It is demonstrated that IFN-γ is essential for control of chronic vascular pathology induced by γHV68 and suggested γ-herpesviruses as candidate etiologic agents for human vasculitis.
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Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105–125

Aimin Li, +5 more
- 24 Jan 2007 - 
TL;DR: Transgenic mice that express a form of murine PrP deleted for a conserved block of 21 amino acids (residues 105–125) in the unstructured, N‐terminal tail of the protein develop a severe neurodegenerative illness that was lethal within 1 week of birth.