Caihong Wang

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The accumulating evidence that prenatal exposure to a wide variety of viral and bacterial infections - or simply inflammation - may subtly alter fetal brain development, leading to neuropsychiatric consequences for the child later in life is presented.

TL;DR: It is found that Atg16L1 mutant mice are resistant to intestinal disease induced by the model bacterial pathogen Citrobacter rodentium, and gene variants affecting the autophagy pathway may have been evolutionarily maintained to protect against certain life-threatening infections.

TL;DR: The results show that Atg16L1 deficiency confers protection in vivo to the host against both acute and latent UPEC infection, suggest that deficiency in a key autophagy protein can be protective against infection in an animal model of one of the most common diseases of women worldwide, and may have significant clinical implications for understanding the etiology of recurrent UTIs.