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Ivana Bjedov

Researcher at University College London

Publications -  33
Citations -  8677

Ivana Bjedov is an academic researcher from University College London. The author has contributed to research in topics: Autophagy & TOR Serine-Threonine Kinases. The author has an hindex of 19, co-authored 29 publications receiving 7471 citations. Previous affiliations of Ivana Bjedov include University of Paris & French Institute of Health and Medical Research.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

Ivana Bjedov, +6 more
- 06 Jan 2010 - 
TL;DR: It is shown here that feeding rapamycin to adult Drosophila produces the life span extension seen in some TOR mutants, and analysis of the underlying mechanisms revealed thatRapamycin increased longevity specifically through the TORC1 branch of the TOR pathway, through alterations to both autophagy and translation.
Journal ArticleDOI

Stress-Induced Mutagenesis in Bacteria

Ivana Bjedov, +15 more
- 30 May 2003 - 
TL;DR: It is suggested that irrespective of the causes of their emergence, stress-induced mutations participate in adaptive evolution and could be a by-product of genetic strategies for improving survival under stress.
Journal ArticleDOI

Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network.

Linda Partridge, +3 more
- 01 May 2011 - 
TL;DR: Cellular detoxification pathways, increased autophagy and altered protein synthesis have all been implicated in increased lifespan from reduced IIS/TOR activity, with the role of defence against oxidative stress unresolved.
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Autophagy in healthy aging and disease

Yahyah Aman, +18 more
TL;DR: A recent review as discussed by the authors examines several emerging features of autophagy and postulates how they may be linked to aging as well as to the development and progression of disease, and discusses current preclinical evidence arguing for the use of auto-ophagy modulators as suppressors of age-related pathologies such as neurodegenerative diseases.