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Mohamed Amessou

Researcher at Wayne State University

Publications -  35
Citations -  7378

Mohamed Amessou is an academic researcher from Wayne State University. The author has contributed to research in topics: Endosome & Endocytic cycle. The author has an hindex of 21, co-authored 33 publications receiving 6832 citations. Previous affiliations of Mohamed Amessou include French Institute of Health and Medical Research & Paris Diderot University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

Sandra Rebouissou, +15 more
- 08 Jan 2009 - 
TL;DR: The recurrent gain-of-function gp130 mutations in these human hepatocellular adenomas fully explains activation of the acute inflammatory phase observed in tumourous hepatocytes, and suggests that similar alterations may occur in other inflammatory epithelial tumours with STAT3 activation.
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Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

Camilla Pilati, +18 more
- 04 Jul 2011 - 
TL;DR: Somatic STAT3 mutations present in a subset of inflammatory hepatocellular adenomas result in the generation of constitutively active STAT3 proteins that homodimerize independently of IL-6 stimulation.
Journal Article

Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes

Agnès Saint-Pol, +10 more
- 01 Apr 2004 - 
TL;DR: It is shown that for Shiga toxin, retrograde sorting on early/recycling endosomes depends on clathrin and epsinR, but not AP1, while EpsinR was also involved in retrograde transport of two endogenous proteins, TGN38/46 and mannose 6-phosphate receptor.
Journal ArticleDOI

Clathrin Adaptor epsinR Is Required for Retrograde Sorting on Early Endosomal Membranes

Agnès Saint-Pol, +10 more
- 01 Apr 2004 - 
TL;DR: In this article, the function of clathrin and that of two proteins that interact with it, AP1 and epsinR, was found to be independent and -dependent in the retrograde transport of Shiga toxin to the trans-Golgi network.