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Christoph Becker

Researcher at University of Erlangen-Nuremberg

Publications -  172
Citations -  27085

Christoph Becker is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Colitis & Immune system. The author has an hindex of 61, co-authored 154 publications receiving 23410 citations. Previous affiliations of Christoph Becker include University of Mainz & Technische Universität München.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Gabriela Bindea, +30 more
- 17 Oct 2013 - 
TL;DR: The immune landscape in human colorectal cancer is revealed and the major hallmarks of the microenvironment associated with tumor progression and recurrence are revealed.
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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

Raja Atreya, +22 more
- 01 May 2000 - 
TL;DR: Assessment of the contribution of the pro-inflammatory cytokine interleukin (IL)-6 to the increased resistance of mucosal T cells against apoptosis in Crohn disease indicates that a pathway of T-cell activation driven by IL-6–sIL-6R contributes to the perpetuation of chronic intestinal inflammation.
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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7.

Massimo Fantini, +5 more
- 01 May 2004 - 
TL;DR: It is demonstrated that TGF-β induces a regulatory phenotype in CD4+CD25− T cells through the induction of Foxp3 and a positive autoregulatory loop of T GF-β signaling due to the absence of Smad7.
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Epithelial NEMO links innate immunity to chronic intestinal inflammation

Arianna Nenci, +12 more
- 29 Mar 2007 - 
TL;DR: It is demonstrated that a primary NF-κB signalling defect in intestinal epithelial cells disrupts immune homeostasis in the gastrointestinal tract, causing an inflammatory-bowel-disease-like phenotype.