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Jane E. Ishmael

Researcher at Oregon State University

Publications -  49
Citations -  7143

Jane E. Ishmael is an academic researcher from Oregon State University. The author has contributed to research in topics: Myosin & Myosin light-chain kinase. The author has an hindex of 20, co-authored 44 publications receiving 6521 citations. Previous affiliations of Jane E. Ishmael include University of Maryland, Baltimore & Oregon Health & Science University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Isolation of a Novel Family of C2H2 Zinc Finger Proteins Implicated in Transcriptional Repression Mediated by Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF) Orphan Nuclear Receptors

TL;DR: Two novel and related C2H2 zinc finger proteins that are highly expressed in the brain, CTIP1 and CTIP2 (COUPTF-interacting proteins1 and 2, respectively), were isolated and shown to interact with all members of the chicken ovalbumin upstream promoter transcription factor (Coup-TF) subfamily of orphan nuclear receptors.
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p300 Functions as a Coactivator for the Peroxisome Proliferator-activated Receptor α

TL;DR: The integrator protein, p300, was demonstrated to interact with mouse peroxisome proliferator-activated receptor α in a ligand-enhanced manner and can be considered a bona fide coactivator for this nuclear receptor.
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Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression.

TL;DR: When these ligands were tested for teratogenic effects on zebra fish and Xenopus embryos, it was found that coadministration of the RXR and RAR ligands caused more severe abnormalities in these embryos than either ligand alone, providing biological support for the synergistic action of the two ligands.
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CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis

TL;DR: The results support the selective contributions of both CTIP1 and CTIP2 in the development and function of both the central nervous and immune systems and the importance of future investigations to define the function(s) of both proteins.