Rosanna Parlato

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The data indicate that in embryonic life TSH does not play an equivalent role in controlling gland growth as in the adult thyroid, and suggest that the major role of the TSH/TSHR pathway is in controlling genes involved in iodide metabolism such as sodium/iodide symporter and thyroperoxidase.

TL;DR: It is reported that in midbrain slices of cocaine-treated mice, synaptic transmission was no longer strengthened when GluR1 or NR1 was abolished, while in the respective mice the drug still induced normal conditioned place preference and locomotor sensitization.

TL;DR: The experiments reported here analyze the expression of the transcription factors Titf1, Hhex, Pax8, and Foxe1 in the thyroid primordium of null mutants of each of them and provide the first evidence of gene expression programs, controlled by a hierarchy of transcription factors expressed inThe thyroid presumptive gut domain and directing the progression of thyroid morphogenesis.

TL;DR: It is demonstrated that CREB regulates specific phases of adult neurogenesis in the subventricular zone/olfactory bulb (SVZ/OB) system, and this finding is supported by peripheral afferent denervation experiments resulting in downregulation of CREB phosphorylation in neuroblasts, which appears heavily impaired.