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Michael N. Sack

Researcher at National Institutes of Health

Publications -  145
Citations -  16742

Michael N. Sack is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Mitochondrion & SIRT3. The author has an hindex of 55, co-authored 135 publications receiving 15105 citations. Previous affiliations of Michael N. Sack include Georgetown University Medical Center & University of Cape Town.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

Ariel C. Bulua, +8 more
- 14 Mar 2011 - 
TL;DR: ROS generated by mitochondrial respiration are needed for optimal proinflammatory cytokine production in healthy cells, and are elevated in cells from patients with an autoinflammatory disorder.
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Fatty Acid Oxidation Enzyme Gene Expression Is Downregulated in the Failing Heart

Michael N. Sack, +5 more
- 01 Dec 1996 - 
TL;DR: Findings identify a gene regulatory pathway involved in the control of cardiac energy production during the development of HF, which is thought to maintain aerobic energetic balance.
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Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling

Anne K. Jonassen, +3 more
- 07 Dec 2001 - 
TL;DR: Insulin administration at reperfusion reduces myocardial infarction, is dependent on early administration during reperfusions, and is mediated via Akt and p70s6 kinase dependent signaling pathway.
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Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women

Michael N. Sack, +2 more
- 29 Jan 1994 - 
TL;DR: An antioxidant effect of physiological levels of 17 beta-oestradiol, which may contribute to an anti-atherogenic action is shown in 18 postmenopausal women.