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Martin E. Fernandez-Zapico

Researcher at Mayo Clinic

Publications -  231
Citations -  14148

Martin E. Fernandez-Zapico is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Pancreatic cancer & Transcription factor. The author has an hindex of 47, co-authored 205 publications receiving 12174 citations. Previous affiliations of Martin E. Fernandez-Zapico include University of Saint Mary & McGill University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

Andrew D. Rhim, +17 more
- 16 Jun 2014 - 
TL;DR: De deleting Shh in a well-defined mouse model of PDAC demonstrated that some components of the tumor stroma can act to restrain tumor growth, and administration of VEGFR blocking antibody selectively improved survival of Shh-deficient tumors.
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Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells

Andrei V. Ougolkov, +4 more
- 15 Mar 2005 - 
TL;DR: It is shown that pancreatic cancer cells contain a pool of active GSK-3beta and that pharmacologic inhibition of G SK-3 kinase activity using small molecule inhibitors or genetic depletion of GK3beta by RNA interference leads to decreased cancer cell proliferation and survival.
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Transcriptional suppression of mir‐29b‐1/mir‐29a promoter by c‐Myc, hedgehog, and NF‐kappaB

Justin L. Mott, +6 more
- 01 Aug 2010 - 
TL;DR: In addition to c‐Myc, mir‐29 expression can be suppressed by hedgehog signaling and inflammatory pathways, both commonly activated in the genesis of human malignancies.
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Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.

Bernadette Neve, +26 more
- 29 Mar 2005 - 
TL;DR: Functional and genetic analyses reveal that KLF11 plays a role in the regulation of pancreatic beta cell physiology, and its variants may contribute to the development of diabetes.