Edésio José Tenório de Melo

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: A new series of 2-[(phenylmethylene)hydrazono]-4-oxo-3-phenyl-5-thiazolidineacetic acids (2a-p) have been synthesized and promoted decreases in the percentage of infected cells leading to parasite elimination and more effective toxicity against intracellular parasites.

TL;DR: The present studies showed that thiosemicarbazones 2 and 4-thiazolidinone derivatives 3 were effective against intracellular T. gondii.

TL;DR: It was shown that most of the compounds in this study have a better performance against intracellular tachyzoites and the majority of the tested compounds show excellent anti-T.

TL;DR: The F3 fraction, rich in peptides, inhibited the growth of yeasts Saccharomyces cerevisiae and caused several morphological changes in different yeasts, such as cell wall disorganization, bud formation as well as the formation of pseudohyphae.