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Victor H. Villar

Researcher at University of Bordeaux

Publications -  26
Citations -  5834

Victor H. Villar is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Medicine & Autophagy. The author has an hindex of 11, co-authored 21 publications receiving 5276 citations. Previous affiliations of Victor H. Villar include University of Chile & French Institute of Health and Medical Research.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion.

Nicolás Tobar, +3 more
- 05 Mar 2010 - 
TL;DR: ROS-NFκΒ acts as the crucial signal in TGF-β1-induced uPA and MMP-9 expression thereby mediating the enhancement of cellular malignity by TGF -β1.
Journal ArticleDOI

Glutaminolysis and autophagy in cancer.

Victor H. Villar, +3 more
- 09 Jun 2015 - 
TL;DR: A combination of therapies targeting simultane-ously cell signaling, cancer metabolism, and autophagy can solve therapy resistance and tumor relapse problems, commonly observed in patients treated with most of the current targeted therapies.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 - 
Journal ArticleDOI

mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation.

Victor H. Villar, +10 more
- 23 Jan 2017 - 
TL;DR: It is shown that m TORC1 also presents tumour suppressor features in conditions of nutrient restrictions and the ability of mTORC1 to activate apoptosis is mediated by the adaptor protein p62, and the role of autophagy as a survival mechanism upon rapamycin treatment is highlighted.