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Miriam Cnop

Researcher at Université libre de Bruxelles

Publications -  174
Citations -  21226

Miriam Cnop is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Unfolded protein response & Beta cell. The author has an hindex of 54, co-authored 153 publications receiving 18510 citations. Previous affiliations of Miriam Cnop include Vrije Universiteit Brussel & University of Washington.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex.

TL;DR: It is suggested that adiponectin concentrations are determined by intra-abdominal fat mass, with additional independent effects of age and sex, and could link intra- abdominalFat with insulin resistance and an atherogenic lipoprotein profile.
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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.

TL;DR: Cytokines and nutrients trigger beta-cell death by fundamentally different mechanisms, namely an NF-kappaB-dependent mechanism that culminates in caspase-3 activation for cytokines and anNF-kappB-independent mechanism for nutrients.
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The role for endoplasmic reticulum stress in diabetes mellitus.

TL;DR: This review addresses the transition from physiology to pathology, namely how and why the physiological UPR evolves to a proapoptotic ER stress response and which defenses are triggered by beta-cells against these challenges.
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Endoplasmic reticulum stress, obesity and diabetes

TL;DR: Ways in which ER stress operates as a common molecular pathway in the pathogenesis of obesity and diabetes are discussed.