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Dongxu Fu

Researcher at Queen's University Belfast

Publications -  27
Citations -  6384

Dongxu Fu is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Diabetic retinopathy & Type 2 diabetes. The author has an hindex of 16, co-authored 26 publications receiving 5723 citations. Previous affiliations of Dongxu Fu include University of Oklahoma Health Sciences Center & Chinese National Human Genome Center.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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cGAS drives noncanonical-inflammasome activation in age-related macular degeneration

Nagaraj Kerur, +45 more
- 01 Jan 2018 - 
TL;DR: It is demonstrated that RPE degeneration in human-cell-culture and mouse models is driven by a noncanonical-inflammasome pathway that activates caspase-4, gasdermin D, interferon-β, and cGAS levels were elevated in the RPE in human eyes with geographic atrophy, and an unexpected role of cGas in responding to mobile-element transcripts is highlighted.
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Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome

Arpita Basu, +7 more
- 01 Jul 2010 - 
TL;DR: Short-term freeze-dried strawberry supplementation improved selected atherosclerotic risk factors, including dyslipidemia and circulating adhesion molecules in subjects with metabolic syndrome, and these results need confirmation in future trials.
Journal ArticleDOI

Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy.

Dongxu Fu, +8 more
- 31 Aug 2012 - 
TL;DR: Cell culture, animal, and human data suggest that oxidative stress and ER stress are induced by modified LDL, and are implicated in pericyte loss in DR.
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Freeze-Dried Strawberries Lower Serum Cholesterol and Lipid Peroxidation in Adults with Abdominal Adiposity and Elevated Serum Lipids

Arpita Basu, +5 more
- 01 Jun 2014 - 
TL;DR: In general, strawberry intervention did not affect any measures of adiposity, blood pressure, glycemia, and serum concentrations of HDL cholesterol and triglycerides, C-reactive protein, and adhesion molecules.