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Lisa M Lindqvist

Researcher at Walter and Eliza Hall Institute of Medical Research

Publications -  45
Citations -  8405

Lisa M Lindqvist is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Eukaryotic translation & Eukaryotic initiation factor. The author has an hindex of 28, co-authored 44 publications receiving 7426 citations. Previous affiliations of Lisa M Lindqvist include University of Melbourne & CSL Limited.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A

Marie-Eve Bordeleau, +9 more
- 12 Mar 2006 - 
TL;DR: This study demonstrates the feasibility of selectively targeting members of the DEAD-box helicase family with small-molecule inhibitors and shows that poliovirus replication is delayed when infected cells are exposed to hippuristanol.
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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

Stephanie A. Conos, +21 more
- 07 Feb 2017 - 
TL;DR: It is shown that MLKL-mediated NLRP3 and caspase-1 activation and the secretion of the proinflammatory cytokine IL-1β is a major determinant of necroptotic-derived inflammatory signals, and the findings suggest that NL RP3 and IL- 1β may be relevant therapeutic targets in MLK lysis-driven diseases.
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Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.

Marie-Eve Bordeleau, +10 more
- 01 Jul 2008 - 
TL;DR: It is established that targeting translation initiation can restore drug sensitivity in vivo and provide an approach to modulating chemosensitivity.
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Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

Marie Eve Bordeleau, +9 more
- 26 Jul 2005 - 
TL;DR: It is suggested that proper control of eIF4A helicase activity is necessary for efficient ribosome binding and the feasibility of selectively targeting DEAD-box RNA helicases with small molecules is demonstrated.