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Ian G. Mills

Researcher at University of Oxford

Publications -  292
Citations -  20358

Ian G. Mills is an academic researcher from University of Oxford. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 55, co-authored 260 publications receiving 17637 citations. Previous affiliations of Ian G. Mills include University of Cambridge & Oslo University Hospital.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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BAR domains as sensors of membrane curvature: the amphiphysin BAR structure

Brian J. Peter, +6 more
- 23 Jan 2004 - 
TL;DR: The structure of the Drosophila amphiphysin BAR domain is solved and it is predicted that BAR domains are in many protein families, including sorting nexins, centaurins, and oligophrenins.
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Curvature of clathrin-coated pits driven by epsin

Marijn G. J. Ford, +6 more
- 26 Sep 2002 - 
TL;DR: It is shown here that epsin 1 directly modifies membrane curvature on binding to PtdIns(4,5)P2 in conjunction with clathrin polymerization, and it is proposed that this helix is inserted into one leaflet of the lipid bilayer, inducing curvature.
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The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Charles E. Massie, +25 more
- 06 Jul 2011 - 
TL;DR: Cal calcium/calmodulin‐dependent protein kinase kinase 2 is highlighted, which it is shown is overexpressed in prostate cancer and regulates cancer cell growth via its unexpected role as a hormone‐dependent modulator of anabolic metabolism.
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GTPase activity of dynamin and resulting conformation change are essential for endocytosis.

Bruno Marks, +6 more
- 08 Mar 2001 - 
TL;DR: It is shown that oligomerization and GTP binding alone, by dynamin, are not sufficient for endocytosis in vivo, and efficient GTP hydrolysis and an associated conformational change are also required.