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Chuangui Wang

Researcher at Shanghai Jiao Tong University

Publications -  68
Citations -  8822

Chuangui Wang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Acetylation & DNA damage. The author has an hindex of 36, co-authored 55 publications receiving 7885 citations. Previous affiliations of Chuangui Wang include East China Normal University & Huazhong University of Science and Technology.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.

TL;DR: It is shown that the cell-cycle and apoptosis regulator E2F1 induces SirT1 expression at the transcriptional level and knockdown ofSirT1 by small interference RNA increases E1F1 transcriptional and apoptotic functions.
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MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

TL;DR: Evidence is presented that MDM2 interacts with the nuclear corepressor KAP1, a RING domain ubiquitin E3 ligase and a major regulator of the p53 tumor suppressor that contributes to p53 functional regulation.
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A Photoelectrochemical Immunosensor Based on Au-Doped TiO2 Nanotube Arrays for the Detection of α-Synuclein

TL;DR: A photoelectrochemical immunosensor for the detection of α-SYN showed high sensitivity, stability, reproducibility, and could become a promising technique for protein detection.
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SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

TL;DR: It is found that SirT1 knockdown by short hairpin RNA accelerates tumor xenograft formation by HCT116 cells, whereasSirT1 overexpression inhibits tumor formation, and pharmacological inhibition of SirT 1 stimulates cell proliferation under conditions of growth factor deprivation.