Marco Antonio Meraz-Ríos

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Clinical trials and animal models with non-steroidal anti-inflammatory drugs (NSAIDs) indicate that these drugs may decrease the risk of developing AD and apparently reduce Aβ deposition.

TL;DR: It is proposed that these molecules, together with IL-10 and prostanoids, are key factors to induce Ag-specific tolerance in memory T cells.

TL;DR: In this article, the physiological function of Tau protein and its abnormal pathological behavior when this protein is self-assemble into pathological filaments was analyzed, and the authors emphasized the possible phenomena implicated in the formation of these oligomers.

TL;DR: The recent advances in tau oligomer research are discussed, their implications on AD and other tauopathies, the mechanisms of tau turnover by the principal protein clearance systems (the proteasome and autophagy), and the potential use of tAU oligomers as drug targets for the development of new therapeutic approaches are discussed.