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Yujie Chen

Researcher at Third Military Medical University

Publications -  88
Citations -  7249

Yujie Chen is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Medicine & Subarachnoid hemorrhage. The author has an hindex of 25, co-authored 68 publications receiving 6224 citations. Previous affiliations of Yujie Chen include Loma Linda University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Activation of Dopamine D2 Receptor Suppresses Neuroinflammation Through αB-Crystalline by Inhibition of NF-κB Nuclear Translocation in Experimental ICH Mice Model

Yang Zhang, +7 more
- 01 Sep 2015 - 
TL;DR: DRD2 agonists inhibited neuroinflammation and attenuated brain injury after ICH, which is probably mediated by CRYAB and enhanced cytoplasmic binding activity with NF-&kgr;B.
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Norrin Protected Blood–Brain Barrier Via Frizzled-4/β-Catenin Pathway After Subarachnoid Hemorrhage in Rats

Yujie Chen, +8 more
- 01 Feb 2015 - 
TL;DR: Norrin protected blood–brain barrier integrity and improved neurological outcome after SAH, and the action of Norrin appeared mediated by Frizzled-4 receptor activation, which promoted &bgr;-catenin nuclear translocation, which then enhanced Occludin, VE-Cadherin, and ZO-1 expression.
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Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats.

Hengli Zhao, +10 more
- 18 Aug 2017 - 
TL;DR: Results indicated endogenous H2S synthesis was impaired after ICH, which plays a pivotal role in the P2X7R/NLRP3 inflammasome-associated neuroinflammatory response in the pathogenesis of secondary brain injury.
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P2X7 receptor antagonism inhibits p38 mitogen-activated protein kinase activation and ameliorates neuronal apoptosis after subarachnoid hemorrhage in rats.

Sheng Chen, +6 more
- 01 Dec 2013 - 
TL;DR: Brilliant blue G significantly improved neurobehavioral function and ameliorated brain water content at 24 and 72 hours after subarachnoid hemorrhage and inhibiting P2X7 receptor small interfering RNA can prevent early brain injury via p38 mitogen-activated protein kinase after subArachnoids hemorrhage.