Ligia C. Gomes

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is shown that mitochondrial morphology determines the cellular response to macroautophagy, and regulated changes in mitochondrial morphology determine the fate of the cell during autophagic degradation.

TL;DR: It is demonstrated that the efficiency of mitochondria-dependent cell growth depends on cristae shape and, accordingly, RCS assembly emerges as a link between membrane morphology and function.

TL;DR: It is shown that the mitochondria are removed through autophagy system and that changes in mitochondrial network occur in atrophying muscles, indicating that disruption of the mitochondrial network is an essential amplificatory loop of the muscular atrophy programme.

TL;DR: This review focuses on the emerging molecular mechanisms of pathogen elimination by autophagy (a process known as xenophagy) and on the strategies developed by pathogens to subvertautophagy.