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Idil Orhon

Researcher at University Medical Center Groningen

Publications -  12
Citations -  7079

Idil Orhon is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 9, co-authored 11 publications receiving 6069 citations. Previous affiliations of Idil Orhon include University of Paris & French Institute of Health and Medical Research.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion.

Mario Mauthe, +9 more
- 20 Jul 2018 - 
TL;DR: It is shown that CQ mainly inhibits autophagy by impairing autophagosome fusion with lysosomes rather than by affecting the acidity and/or degradative activity of this organelle.
Journal ArticleDOI

Functional interaction between autophagy and ciliogenesis

Olatz Pampliega, +9 more
- 10 Oct 2013 - 
TL;DR: This work shows that part of the molecular machinery involved in ciliogenesis also participates in the early steps of the autophagic process, and proposes that basal autophagy regulates ciliary growth through the degradation of proteins required for intraflagellar transport.
Journal ArticleDOI

p53 represses autophagy in a cell cycle-dependent fashion.

Ezgi Tasdemir, +6 more
- 01 Oct 2008 - 
TL;DR: It is shown by epistatic analysis that p53 inhibition results in a maximum level of autophagy that cannot be further enhanced by a variety of different autophagic inducers including lithium, tunicamycin-induced stress of the endoplasmic reticulum (ER) or inhibition of Bcl-2 and BCl-XL with the BH3 mimetic ABT737.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -