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Hirosato Mashima

Researcher at Jichi Medical University

Publications -  101
Citations -  6546

Hirosato Mashima is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 21, co-authored 86 publications receiving 5923 citations. Previous affiliations of Hirosato Mashima include University of Tokyo & Akita University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Distinct Roles of Smad2-, Smad3-, and ERK-dependent Pathways in Transforming Growth Factor-β1 Regulation of Pancreatic Stellate Cellular Functions

Hirohide Ohnishi, +12 more
- 05 Mar 2004 - 
TL;DR: TGF-β1 differentially regulates PSC activation, proliferation, and TGF- β1 mRNA expression through Smad2, Smad3, and ERK-dependent pathways, respectively.
Journal ArticleDOI

Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells ☆

Hiroshi Yasuda, +5 more
- 02 Mar 2007 - 
TL;DR: It is demonstrated that EGFR-ERK1/2 is activated following treatment of AGS human gastric carcinoma cells with bile acids, and results suggest that in AGS cells, DC transactivates EGFR through M-BAR- and ADAM/HB-EGF-dependent mechanisms.
Journal ArticleDOI

Autocrine loop between TGF-β1 and IL-1β through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells

Hiroyoshi Aoki, +16 more
- 01 Apr 2006 - 
TL;DR: Pancreatic stellate cells (PSCs) are activated during pancreatitis and promote pancreatic fibrosis by producing and secreting ECMs such as collagen and fibronectin.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -