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Josef M. Penninger

Josef M. Penninger

Researcher at University of British Columbia

Publications - 742

Citations - 123402

Josef M. Penninger is an academic researcher from University of British Columbia. The author has contributed to research in topics: RANKL & T cell. The author has an hindex of 154, co-authored 700 publications receiving 107295 citations. Previous affiliations of Josef M. Penninger include Austrian Academy of Sciences & Amgen.

Papers

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

- 21 Jan 2016 -

Autophagy

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TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

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Molecular characterization of mitochondrial apoptosis-inducing factor

Santos A. Susin,Hans K. Lorenzo,Naoufal Zamzami,Isabel Marzo,Bryan E. Snow,Joan Mangion,Etienne Jacotot,Paola Costantini,Markus Loeffler,Nathanael Larochette,David R. Goodlett,Ruedi Aebersold,David P. Siderovski,Josef M. Penninger,Guido Kroemer +14 moreCentre national de la recherche scientifique,Pasteur Institute,Amgen,University of Washington,Ontario Institute for Cancer Research

- 04 Feb 1999 -

Nature

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TL;DR: The identification and cloning of an apoptosis-inducing factor, AIF, which is sufficient to induce apoptosis of isolated nuclei is reported, indicating that AIF is a mitochondrial effector of apoptotic cell death.

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Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster,Magdalena Renner,Carol Anne Martin,Daniel Wenzel,Louise S. Bicknell,Matthew E. Hurles,Tessa Homfray,Josef M. Penninger,Andrew P. Jackson,Juergen A. Knoblich +9 moreAustrian Academy of Sciences,University of Edinburgh,Wellcome Trust Sanger Institute,St George's, University of London

- 19 Sep 2013 -

Nature

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TL;DR: A human pluripotent stem cell-derived three-dimensional organoid culture system that develops various discrete, although interdependent, brain regions that include a cerebral cortex containing progenitor populations that organize and produce mature cortical neuron subtypes is developed.

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Journal ArticleDOI

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

- 23 Jan 2018 -

Cell Death & Differentiation

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TL;DR: The Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.

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Journal ArticleDOI

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Young-Yun Kong,Hiroki Yoshida,Ildiko Sarosi,Hong-Lin Tan,Emma Timms,Casey Capparelli,Sean Morony,Antonio J. Oliveira-dos-Santos,Gwyneth Van,Annick Itie,Wilson Khoo,Andrew Wakeham,Colin R. Dunstan,David L. Lacey,Tak W. Mak,William J. Boyle,Josef M. Penninger +16 moreUniversity of Toronto,Ontario Institute for Cancer Research,Amgen

- 28 Jan 1999 -

Nature

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TL;DR: OPGL is a new regulator of lymph-node organogenesis and lymphocyte development and is an essential osteoclast differentiation factor in vivo.

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