Bo Yan

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Genetic analysis of the promoter region of SIRT1 gene in sporadic PD patients and ethic-matched healthy controls suggested that genetic variants within the Sirtuis gene promoter may repress Sirt1 gene expression, contributing to PD as a risk factor.

TL;DR: Data provide supportive evidence that mutations in the coding region of the NKX2-5 gene and sequence variants within its promoter region may be among the contributors to the CHD etiology.

TL;DR: The variants identified in MI patients may alter the transcriptional activities of SIRT1 gene promoter, which may change Sirt1 levels, contributing to the MI pathogenesis as a risk factor.