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Chunlai Wu

Researcher at LSU Health Sciences Center New Orleans

Publications -  19
Citations -  6023

Chunlai Wu is an academic researcher from LSU Health Sciences Center New Orleans. The author has contributed to research in topics: Ubiquitin ligase & Autophagy. The author has an hindex of 13, co-authored 19 publications receiving 5512 citations. Previous affiliations of Chunlai Wu include Washington University in St. Louis & Louisiana State University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

Xin Xiong, +9 more
- 04 Dec 2012 - 
TL;DR: Highwire, a conserved axonal E3 ubiquitin ligase, regulates the initiation of axonal degeneration after injury in Drosophila by regulating the levels of the NAD+ biosynthetic enzyme, Nmnat, and the Wnd kinase.
Journal ArticleDOI

Highwire Function at the Drosophila Neuromuscular Junction: Spatial, Structural, and Temporal Requirements

Chunlai Wu, +3 more
- 19 Oct 2005 - 
TL;DR: It is found that presynaptic activity of highwire is both necessary and sufficient to regulate both synapse morphology and physiology, and that highwire may independently regulate the molecular pathways controlling synaptic growth and function.
Journal ArticleDOI

RIM Promotes Calcium Channel Accumulation at Active Zones of the Drosophila Neuromuscular Junction

Ethan R. Graf, +7 more
- 21 Nov 2012 - 
TL;DR: Drosophila RIM (Rab3 interacting molecule) is identified and it is demonstrated that it localizes to active zones at the larval neuromuscular junction and functions to regulate Ca2+ channel accumulation but is not a Rab3 effector for release machinery distribution across release sites.
Journal ArticleDOI

DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth

Chunlai Wu, +2 more
- 15 Aug 2007 - 
TL;DR: The F-box protein DFsn binds the ubiquitin ligase Highwire and is required to down-regulate the levels of the Wallenda/DLK kinase and restrain synaptic terminal growth.