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Paul W. Sylvester

Researcher at University of Louisiana at Monroe

Publications -  161
Citations -  10820

Paul W. Sylvester is an academic researcher from University of Louisiana at Monroe. The author has contributed to research in topics: Mammary tumor & Tocotrienol. The author has an hindex of 43, co-authored 152 publications receiving 10043 citations. Previous affiliations of Paul W. Sylvester include University of Alabama at Birmingham & Michigan State University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Book ChapterDOI

Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability.

TL;DR: The MTT colorimetric assay provides accurate and reliable quantification of viable cell number in proliferation and cytotoxicity studies by controlling for drug treatment effects that may influence cellular metabolism.
Journal ArticleDOI

Antiproliferative and Apoptotic Effects of Tocopherols and Tocotrienols on Preneoplastic and Neoplastic Mouse Mammary Epithelial Cells

TL;DR: Comparative effects of tocopherols and tocotrienols on preneoplastic, neoplastic and highly malignant mouse mammary epithelial cell growth and viability in vitro showed that CL-S1, -SA, and +SA cells preferentially accumulate tocotrianols as compared with tocopHerols, and this may partially explain why tocotianols display greater biopotency than tocop herols.
Journal ArticleDOI

Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells.

TL;DR: Findings suggest that the highly biopotent γ- and δ-tocotrienol isoforms may play a physiological role in modulating normal mammary gland growth, function, and remodeling.
Journal ArticleDOI

Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity.

TL;DR: Findings demonstrate that the antiproliferative effects of γ-tocotrienol result, at least in part, from a reduction in Akt and NFκB activity in neoplastic +SA mammary epithelial cells.