Nikolai Slavov

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: This work develops Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) and validate its ability to identify distinct human cancer cell types based on their proteomes and uses it to quantify over a thousand proteins in differentiating mouse embryonic stem cells.

TL;DR: The Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) method as discussed by the authors was developed to identify distinct human cancer cell types based on their proteomes.

TL;DR: In this article, the authors developed SCoPE2, which substantially increases quantitative accuracy and throughput while lowering cost and hands-on time by introducing automated and miniaturized sample preparation, and demonstrated the potential for inferring transcriptional and post-transcriptional regulation from variability across single cells.

TL;DR: Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) was developed and validated its ability to identify distinct human cancer cell types based on their proteomes, and it was used to quantify over a thousand proteins in differentiating mouse embryonic stem (ES) cells.