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Mohamed Al-Rubeai

Researcher at University College Dublin

Publications -  219
Citations -  12447

Mohamed Al-Rubeai is an academic researcher from University College Dublin. The author has contributed to research in topics: Cell culture & Apoptosis. The author has an hindex of 48, co-authored 219 publications receiving 11651 citations. Previous affiliations of Mohamed Al-Rubeai include University of Birmingham & Cihan University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Selection methods for high-producing mammalian cell lines.

Susan M. Browne, +1 more
- 01 Sep 2007 - 
TL;DR: There is an increasing need for methods for the selection of mammalian cell lines stably expressing recombinant products at high levels in an efficient, cost-effective and high-throughput manner.
Journal ArticleDOI

Cell death in bioreactors : a role for apoptosis

R. P. Singh, +3 more
- 05 Sep 1994 - 
TL;DR: Blockage of the cell cycle of the plasmacytoma and hybridoma cells using thymidine resulted in the induction of apoptosis, which has important implications for the development of cell culture processes that minimize cell division and thereby increase specific productivity.
Journal ArticleDOI

Apoptosis in cell culture.

Mohamed Al-Rubeai, +1 more
- 01 Apr 1998 - 
TL;DR: A growing number of studies have demonstrated that the suppression of apoptosis by the overexpression of anti-apoptosis genes, most notably bcl-2, result in improved culture productivity.
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The effects of agitation intensity with and without continuous sparging on the growth and antibody production of hybridoma cells

Steve Oh, +3 more
- 01 Oct 1989 - 
TL;DR: Cell growth and viability, antibody production, glucose consumption, lactate production and metabolic activity have been measured and found to be unaffected over this range of speeds, and the implications of this speed range on the turbulence parameters have been discussed.