Vladimir Bumbasirevic

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Electrochemically produced GQD irradiated with blue light generates reactive oxygen species, including singlet oxygen, and kill U251 human glioma cells by causing oxidative stress and a genetic inactivation of autophagy-essential LC3B protein partly abrogated the photodynamic cytotoxicity of G QD.

TL;DR: It is suggested that cisplatin‐triggered activation of AMPK and subsequent suppression of mTOR activity can induce an autophagic response that protects tumour cells from cisPlatin‐mediated apoptotic death.

TL;DR: The antidiabetic drug metformin reduces cisplatin in vitro anticancer activity through AMPK-independent upregulation of Akt survival pathway, and warrant caution when considering met formin for treatment of diabetic cancer patients receiving cisPlatin or as a potential adjuvant in cisplin-based chemotherapeutic regimens.

TL;DR: The administration of astrocyte‐induced regulatory T cells markedly alleviated CNS inflammation and clinical symptoms of CNS autoimmunity in rats with experimental allergic encephalomyelitis, indicating that astro Cytes might represent an important mechanism for self‐limitation of excessive inflammation in the brain.